Broad Horizons

Acoustic metamaterials: From local resonances to broad horizons

Within a time span of 15 years, acoustic metamaterials have emerged from academic curiosity to become an active field driven by scientific discoveries and diverse application potentials. This review traces the development of acoustic metamaterials from the initial findings of mass density and bulk modulus frequency dispersions in locally resonant structures to the diverse functionalities afford...

Broad-spectrum human papillomavirus vaccines: new horizons but one step at a time.

This issue of the Journal presents the results of an experimental project describing the technology and the model system to generate novel human papillomavirus (HPV) vaccines. Rather than using the immune capacity of the L1 capsid epitopes, these prototypes are based on the unique properties of the L2 protein of the capsid to induce broad-spectrum (BS) HPV antigenic recognition and the formatio...

NEW HORIZONS New horizons in osteoarthritis

Osteoarthritis (OA) is the most common type of arthritis worldwide and rapidly increasing with ageing populations. It is a major source of pain and disability for individuals and economic burden for health economies. Modern imaging, in particular magnetic resonance imaging (MRI), has helped us to understand that OA is a dynamic remodelling process involving all the structures within the joint. ...

Expanding horizons

Enhanced Horizons

Half-supersymmetric geometries of N = 2 five-dimensional gauged supergravity have recently been fully classified using spinorial geometry techniques. We use this classification to determine all possible regular halfsupersymmetric near-horizon geometries, assuming that all of the gaugeinvariant spinor bilinears are regular at the horizon. Four geometries are found, two of which have been found p...